Health & Wellness, Spartanburg SC
Spartanburg Regional Healthcare System (SRHS) is one of the largest employers in Spartanburg County, with more than 12,000 employees spanning seven counties of the SC Upstate. The flagship Spartanburg Medical Center on East Wood Street operates roughly 600 licensed beds and holds Level I Trauma Center designation — receiving the most critical trauma cases from Spartanburg, Cherokee, Union, Laurens, and neighboring counties. Pelham Medical Center in Greer anchors the Highway 14 and Pelham Road growth corridor, serving the fast-expanding Spartanburg-east and Greer communities. The 2023–2024 Bon Secours divestment reshaped the local landscape: SRHS absorbed the Mary Black Memorial Hospital campus on Skylyn Drive, consolidating acute-care under one regional umbrella.
The Upstate healthcare ecosystem layers city institutions, county facilities, and multi-county referral networks. SRHS anchors the system through Spartanburg Medical Center and Pelham Medical Center, with the Mary Black campus now integrated after the Bon Secours transition. Bon Secours St. Francis Eastside in Greenville remains part of the broader regional referral network for specialized care. Prisma Health Upstate, headquartered in Greenville, maintains Spartanburg-area presence and serves as a competitive alternative for certain specialty services. Veterans access care at the Spartanburg VA Outpatient Clinic on the city's north side. Free and sliding-scale care is provided by ReGenesis Healthcare and St. Luke's Free Medical Clinic. Mental health services are delivered through the Spartanburg Area Mental Health Center, with peer advocacy via NAMI Piedmont.
The regulatory landscape shifted in 2024 when SC DHEC split into two agencies: the SC Department of Public Health (SCDPH) now handles immunization mandates, school health requirements, and healthcare facility licensing, while SCDES (the Department of Environmental Services) manages environmental permitting and air quality. In USDA hardiness zone 7b–8a, local allergens — oak, pine, and ragweed — drive significant ENT and asthma caseloads. The opioid and fentanyl crisis remains acute: Spartanburg County Coroner data tracks fentanyl-involved deaths annually, and DAODAS partner networks distribute Naloxone at pharmacies and community sites across the county. Medicaid expansion remains unresolved at the SC Statehouse. Heat illness is a recurring hazard for outdoor and warehouse workers throughout BMW, Michelin, and the broader Spartanburg County industrial base.
HERESpartanburg covers the full Upstate health spectrum: Spartanburg Medical Center expansion projects, drug shortages at local pharmacies, insurance rate fights before SC regulators, and free-clinic schedules serving Inman, Chesnee, and Pacolet. We publish mental health resource directories linking to the Spartanburg Area Mental Health Center and NAMI Piedmont, track ReGenesis Healthcare sliding-scale availability, and map Naloxone and opioid-treatment access points across the county. Cancer care coverage spans Gibbs Cancer Center and its partnership with MUSC Hollings in Charleston for clinical trials. We track Medicare Advantage open-enrollment windows, BLS class schedules, and SC Department of Public Health (SCDPH) advisories as they affect Spartanburg County residents. If it touches Upstate health, it's HERE.
Upstate Healthcare Updates
Health & Wellness Guides
Find Local Providers
| Provider / Practice | Category | Area | Status | Phone |
|---|---|---|---|---|
|
Spartanburg Regional Medical Center
101 E Wood St, Spartanburg SC
|
Hospital & ER | Downtown Spartanburg | New Patients Medicaid 24/7 ER | (864) 560-6000 |
|
Pelham Medical Center
250 Westmoreland Rd, Greer SC
|
Hospital | Greer / Pelham | New Patients 24/7 ER | (864) 530-6000 |
|
Prisma Health Greer Memorial Hospital
830 S Buncombe Rd, Greer SC
|
Hospital & ER | Greer / Taylors | New Patients Medicaid 24/7 ER | (864) 797-8000 |
|
Spartanburg Regional Urgent Care
Multiple Spartanburg County locations
|
Urgent Care | Countywide | Walk-In Welcome Medicaid | (864) 560-6000 |
|
ReGenesis Health Care
10 Fairforest Rd & multiple sites, Spartanburg SC
|
Community Health Center | Spartanburg City | New Patients Medicaid Sliding Scale | (864) 814-4000 |
|
USC Upstate Student Health Services
800 University Way, Spartanburg SC
|
University Health | USC Upstate Campus | Students Only | (864) 503-5191 |
|
NAMI Spartanburg County
In-person meetings & virtual support
|
Mental Health | Multiple / Virtual | Open Enrollment | namisc.org |
|
Spartanburg Regional Behavioral Health
101 E Wood St, Spartanburg SC
|
Mental Health | Downtown Spartanburg | New Patients Medicaid | (864) 560-6000 |
|
Westside Family Dental
1526 W Main St, Spartanburg SC
|
Dental — General | Westside Spartanburg | New Patients Medicaid | (864) 583-7401 |
|
ReGenesis Health Care — Dental
10 Fairforest Rd, Spartanburg SC
|
Dental — Sliding Scale | Spartanburg City | New Patients Medicaid Sliding Scale | (864) 814-4000 |
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Gold’s Gym Spartanburg
8150 Warren H. Abernathy Hwy, Spartanburg SC
|
Fitness / Gym | North Spartanburg | Open Membership | (864) 574-4653 |
|
Croft State Park
450 Croft State Park Rd, Spartanburg SC
|
Fitness — Trails / Outdoor | East Spartanburg | Free / Day Pass | (864) 585-1283 |
|
CVS Pharmacy — MinuteClinic
Multiple Spartanburg County locations
|
Pharmacy & MinuteClinic | Countywide | Walk-In Clinic Medicaid | cvs.com/minuteclinic |
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Anytime Fitness — Spartanburg
Multiple Spartanburg locations
|
Fitness / Gym | Multiple | Open Membership 24/7 Access | anytimefitness.com |
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Planet Fitness Spartanburg
1415 W O Ezell Blvd, Spartanburg SC
|
Fitness / Gym | Westside Spartanburg | Open Membership | (864) 541-4040 |
Continuing Education & Caregiver Support
Frequently Asked Questions
Latest Spartanburg Health News
FDA withdraws Krazati Erbitux colorectal approval
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Abbott TactiFlex Duo ablation catheter approved
The Food and Drug Administration approved Abbott’s TactiFlex Duo Ablation Catheter, Sensor Enabled, a device that combines pulsed-field ablation and radiofrequency energy in a single catheter to treat…
FDA approves Etcamah for ESR1 breast cancer
The Food and Drug Administration on September 4, 2026 granted accelerated approval to Etcamah (camizestrant) in combination with a CDK4/6 inhibitor for adults with hormone-receptor-positive, HER2-negative locally advanced…
Kofinas garlic olive oil recalled by FDA
LMSI LLC, doing business as Kofinas Olive Oil, is voluntarily recalling its Garlic Mediterranean Infused Extra Virgin Olive Oil because the product contains a garlic essential oil that…
FDA approves RASONQUE for pancreatic cancer
The Food and Drug Administration approved RASONQUE (daraxonrasib), the first targeted therapy in a new class of RAS inhibitors, for adults with metastatic pancreatic adenocarcinoma who have already…
HHS names four permanent senior FDA leaders
The Department of Health and Human Services on September 8, 2026, named four permanent senior leaders at the Food and Drug Administration, filling the top posts at the…
Spring Outdoor Fitness in Spartanburg: Best Trails and Timing for April Workouts
April in Spartanburg is made for outdoor fitness. The conditions that define mid-spring in the Upstate — mild temperatures, low humidity, blooming trails, long daylight hours — combine…
SC Measles Outbreak Nearing End: What Spartanburg Families Need to Do Now
South Carolina’s measles outbreak — which grew to 700 confirmed cases and ranked among the most severe in the state’s public health history — appears to be nearing…
Spartanburg Measles Outbreak Nearing End as Case Count Holds at 997 with No New Infections
Published April 14, 2026 at 7:00 PM | By B. Bree Kelley, Business Reporter Zero New Cases Since March 17 as Outbreak End Date Approaches The South Carolina…


